Spero Therapeutics Inc

Spero Therapeutics Inc. a clinical-stage biopharmaceutical company focuses on identifying developing and commercializing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include tebipenem pivoxil hydrobromide (HBr) an oral carbapenem-class antibiotic to treat complicated urinary tract infections including pyelonephritis for adults; SPR206 a direct acting IV-administered agent to treat MDR Gram-negative bacterial infections in the hospital; and SPR720 a novel oral antibiotic for the treatment of non-tuberculous mycobacterial pulmonary disease. It has license agreement with Meiji Seika Pharma Co. Ltd. to support the development of tebipenem HBr; license agreement with Everest Medicines to develop manufacture and commercialize SPR206 in China South Korea and Southeast Asian countries; collaboration agreement with Bill & Melinda Gates Medical Research Institute to develop SPR720 for the treatment of lung infections caused by Mycobacterium tuberculosis; and license agreement with Vertex Pharmaceuticals Incorporated for patents relating to SPR720 as well as SPR719 an active metabolite. Spero Therapeutics Inc. was founded in 2013 and is headquartered in Cambridge Massachusetts.