Corbus Pharmaceuticals Holdings Inc

Corbus Pharmaceuticals Holdings Inc. a biopharmaceutical company develops products to defeat serious illness. It develops CRB-701 an antibody drug conjugate (ADC) that targets the expression of Nectin-4 on cancer cells to release a cytotoxic payload of monomethyl auristatin E (MMAE) which is in Phase I clinical trial; CRB-601 an anti-integrin monoclonal antibody that blocks the activation of TGFß expressed on cancer cells for the treatment of solid tumors; CRB-913 an endocannabinoid small molecule drug for the treatment of obesity and related metabolic diseases; and lenabasum an oral molecule that selectively activates cannabinoid receptor type 2 (CB2) which is in Phase II clinical trial or the treatment of inflammation and fibrosis. It has a licensing agreement with Jenrin Discovery LLC to develop and commercialize the licensed products including the Jenrin library of approximately 600 compounds and multiple issued and pending patent filings. The company was incorporated in 2009 and is based in Norwood Massachusetts.